hACF1/BAZIA is a subunit of the ATP-dependent chromatin-remodelling factor (ACF) complex, and the ISWI CHRAC remodelling complex.
| Institute |
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| Marie Curie Research Institute |
| SKU: | 151582 |
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| Product description: | hACF1/BAZIA is a subunit of the ATP-dependent chromatin-remodelling factor (ACF) complex, and the ISWI CHRAC remodelling complex. In the ACF complex, hACF1/BAZIA influences the nucleosome remodelling activity of the SNF2h ATPase. In the CHRAC complex, hACF1/BAZIA is thought to target CHRAC to heterochromatin. hACF1/BAZIA has several conserved domains including a bromodomain, BAZ, PHD finger, WAC, and WAKZ. |
| Conjugation: | Unconjugated |
| Molecular weight: | 179 kDa |
| Immunogen: | Human peptide conjugated to LPH (hemocyanine from Limulus polyphemus) |
| Cat. #: | 151582 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Genetics |
| Application: | WB |
| Target: | ATP-utilizing chromatin assembly and remodeling factor 1 (ACF1; BAZIA) |
| Reactivity: | Human |
| Clone: | hACF1 BAZIA |
| Host: | Rabbit |
| Class: | Polyclonal |
| Target background: | hACF1/BAZIA is a subunit of the ATP-dependent chromatin-remodelling factor (ACF) complex, and the ISWI CHRAC remodelling complex. In the ACF complex, hACF1/BAZIA influences the nucleosome remodelling activity of the SNF2h ATPase. In the CHRAC complex, hACF1/BAZIA is thought to target CHRAC to heterochromatin. hACF1/BAZIA has several conserved domains including a bromodomain, BAZ, PHD finger, WAC, and WAKZ. |
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| Format: | Liquid |
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| Concentration: | 1.5 mg/ml |
| Storage buffer: | Tris-Glycine buffer, pH7.5, 250mM NaCl |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Poot et al. 2000. EMBO J. 19(13):3377-87. PMID: 10880450. HuCHRAC, a human ISWI chromatin remodelling complex contains hACF1 and two novel histone-fold proteins. |
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