Ovarian cancers often develop resistance to PARP inhibitors. This infographic distils the key concepts behind PARPi response and resistance into a clear visual reference for researchers.
Visual Guide: PARPi Resistance in Ovarian Cancer
Inside the guide:
- DNA repair and its role in PARPi response
- Escape mechanisms: BRCA reversion, fork protection, and more
- Emerging approaches to re-sensitise tumours
- Models that reflect tumour evolution
Why CancerTools.org?
This infographic was developed by CancerTools.org, part of Cancer Research UK. As a non-profit, we provide global access to cancer models from leading academic institutes, with proceeds funding further research.
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