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UM-UC panel: A trusted resource for bladder cancer research

Diverse, well-characterised models to advance discovery and translational impact in bladder cancer

The UM-UC cell line collection brings together 11 patient-derived urothelial carcinoma cell lines (UM-UC-1 through to UM-UC-14), originally developed by Prof. H. Barton Grossman and Dr. Anita Sabichi at the University of Michigan.

Each cell line originates from a different patient, capturing the heterogeneity of bladder cancer and making the collection a robust, reliable tool to support meaningful discoveries and translational progress.

Explore the UM-UC panel
UM-UC-7 Cell Line. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC), UK.

UM-UC-11 Cell Line. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC), UK.


Why the UM-UC panel matters

The UM-UC panel has been extensively characterised in peer-reviewed literature (1-3), providing trusted data to support confident experimental design. These patient-derived cell lines offer:

  1. Diverse patient representation: Capturing a broad spectrum of genetic and clinical backgrounds, the panel reflects the real-world complexity and biology of bladder cancer.
  2. Tumorigenicity data: Enabling translational research by supporting in vivo modelling, mechanism-of-action studies, and validation of therapeutic targets and biomarkers.
  3. Suitability for adenovirus-mediated gene transfer: Facilitating model adaptation and functional studies of specific genes of interest through efficient gene delivery.

Comparison table of UM UC cell lines
Download the UM-UC panel table

Collated Insights for Confident Research

To support your decision-making, we have collated essential data on each cell line, providing a clear overview of their genomic and phenotypic characteristics, helping you select the right model for your studies.

By scientists for scientists, the UM-UC cell line panel was developed to provide a trusted, ready-to-use resource for advancing bladder cancer research. Bringing together 11 well-studied, patient-derived cell lines into a single panel, it offers a powerful tool for reliable, reproducible, and meaningful results.

Access the UM-UC panel
UM-UC-7 Cell Line. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC), UK.

UM-UC-7 Cell Line. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC), UK.

Download the UM-UC panel table

For our commercial customers

Our dedicated licensing team can assist you in any of your commercial enquiries and help to guide you in identifying the right license for your needs. We support partners in the Pharma, Biotechnology and CRO/CDMO industries. Please contact us below:

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References

  1. Sabichi et al. 2006. J Urol. 175(3 Pt 1):1133-7. PMID: 16469639 
  2. Earl et al. 2015. BMC genomics, 16(1), 403.  PMIDP: 25997541 
  3. Zuiverloon et al. 2018. Bladder Cancer,  Apr 26;4(2):169-183, PMID: 29732388 

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