Anti-HIF2A [Hif2a 237] Product

Induction of the Hif regulated genes, as a consequence of the microenvironment or genetic changes, is known to have an important role in the growth of experimental tumours.

Anti-HIF1A [ESEE122] Product

HIF1A has been observed in varying subsets of tumour cells from various solid tumours.

Anti-Maspin [16F7] Product

Monoclonal antibody for Maspin (SERPINB5) recognizing both native and denatured forms forms of Maspin.

Anti-CEACAM5 (CD66e) [3E10-3] Product

CEACAM5 is a glycoprotein involved in cell adhesion and intracellular signaling. It is normally produced during fetal development in the gut, and its production stops before birth. CEA is re-expressed…

FACS analysis on live SNU-5 cells using anti-c-Met 8

Anti-c-Met [8] Product

Aberrant c-Met activation was found to induce tumour development, tumour cell migration and invasion, and the worst and final step in cancer progression, metastasis.

Western blot was performed using anti-sCD40 (soluble) [T8P2G4*A6] applied to Jurkat cell lysates

Anti-sCD40 (soluble) [T8P2G4*A6] mAb Product

CD40 is a 48 kD type I glycoprotein and a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells.

PASD1 Schematic exon structure of the PASD1 gene and the regions used to generate immunogens for the production of PASD1 monoclonal antibodies.

Anti-PASD1 [2ALCC128] Product

PASD1 was originally identified as a target of anti- tumour immune responses in patients with aggressive diffuse large B-cell lymphoma. Subsequent studies have identified PASD1 expression in myeloma patients (both […]

Anti-PAX-FOXO1 [PaxF] Product

Alveolar Rhabdomyosarcoma (ARMS) is an aggressive pediatric cancer and cases with fusion oncoproteins PAX7-FOXO1 and PAX3-FOXO1 have a poor prognosis. Determination of the fusion status is important for RMS diagnostics and therapies. This antibody is specific for the PAX3-FOXO1 and PAX7-FOXO1 and therefore is a valuable tool to study the oncogenesis of ARMS

From Shimazui et al Clin Cancer Res. 1998 Oct;4(10)

Anti-Cadherin 6 [2B6-D8] Product

From Shimazui et al Clin Cancer Res. 1998 Oct;4(10):2419-24. “In many carcinomas, E-cadherin is considered to be a prognostic marker for patient survivals, and its decreased expression is associated with…