Anti-cMyc [9E10] Product

Monoclonal antibody raised against sequence of c-Myc, a proto-oncogene heavily implicated in a variety of (hematopoietic) cancers, which has been used in cancer research to detect and understand the distribution of the c-Myc oncogene product.

Anti-Lewis Y [C14] Product

692/29 showed good anti-tumour responses in vivo and is a strong therapeutic candidate.

Anti-HPV16E7 [TVG 701Y] mAb. Histopathological analysis of the normal and cancer tissues by haematoxylin and eosin staining. HPV-16-E7 protein was detected (arrowheads) by immunohistochemistry. Adapted from Kannan et al. 2017. Histopathological analysis of the normal and cancer tissues by haematoxylin and eosin staining. HPV-16-E7 protein was detected (arrowheads) by immunohistochemistry. Adapted from Kannan et al. 2017.

Anti-HPV16E7 [TVG 701Y] mAb Product

HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively.

Anti-E2F4 [RK13] Product

[…] E2F family plays a crucial role in the control of cell cycle and action of tumour suppressor proteins and is also a target of the transforming proteins of small DNA […]

Summary of the IgG subclasses of five m5T4 specific monoclonal antibodies (mAb; made in 5T4KO mice) recognizing distinct epitopes in the proximal and distal 5T4 extracellular LRR containing domains. (Southgate et al. 2010. PLoS One. 5(4)

Anti-5T4 [B3F1] Product

Monoclonal antibody directed against 5T4, with use as a prognostic aid of tumours.

FACS analysis on live SNU-5 cells using anti-c-Met 17

Anti-c-Met [17] Product

[…] as motility, angiogenesis, morphogenesis, cell survival and cell regeneration. c-Met is abnormally activated in many tumour types. Aberrant c-Met activation was found to induce tumour development, tumour cell migration and […]

Western blot analysis of lysates prepared from U20S cells transfected with myc-MOAP-1 (+) or vector control (-). Detection was performed using an anti-Myc antibody or anti-MOAP-1 [4A12]

Anti-MOAP-1 [4A12] Product

MOAP-1, also known as MAP-1 (Modulator of apoptosis-1) was initially identified as a Bax-associating protein from a yeast two-hybrid screen using Bax as bait. MOAP-1 is enriched in mitochondria and…

Detection of endogenous c-Met in SNU-5 (c-Met positive) and T47D (c-Met negative) cells by immunofluorescence using purified anti-alpha-chain monoclonal antibodies.

Anti-c-Met [12.1] Product

[…] as motility, angiogenesis, morphogenesis, cell survival and cell regeneration. c-Met is abnormally activated in many tumour types. Aberrant c-Met activation was found to induce tumour development, tumour cell migration and […]

Adapted from Gibson FM; Kemshead JT. A monoclonal antibody (FMG25) that can differentiate neuroblastoma from other small round-cell tumours of childhood. Int J Cancer. 1987 May 15;39(5)

Anti-Neuroblastoma [FMG25] Product

[…] rhabdomyosarcoma. May be useful as one of a panel of reagents to detect and remove tumour cells from bone marrow harvested for autologous transplantation. Also cross reacts with normal brain […]

Anti-IFITM1 [IFITM1] Product

IFITM1 will recognise all 3 isoforms of IFITMs ( IFITM1, IFITM2 and IFITM3).