Anti-Keratin 7 & 8 [LDS68] Product

Monoclonal antibody directed against closely related keratin’s 7 and 8, useful in studying epithelial cells and tumours of epithelial origin.

Anti-Keratin 7 & 8 [LDS65] Product

[…] sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. LdS 65 is useful for studies of epithelial cells and tumour origin.

Anti-Keratin 19 [LAS86] Product

Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins…

Anti-CLEC9A [1F6] Product

Monoclonal antibody directed against DNGR-1 marker for CD8+ dendritic cells, which can be exploited for tumour therapy, whilst also recognising necrotic cells.

Immunohistochemical localisation of activated MMP-9 in oesophageal cancer using mAb 4A3

Anti-a-MMP9 [4A3] Product

[…] specific MMPs. Together, the MMPs and TIMPs form a complex biological system strictly controlling degradation of ECM. The MMPs and TIMPs have a significant role in facilitating tumour invasion and metastasis

Anti-CD44v3 [3G5] Product

Monoclonal antibody directed against a marker of tumour metastasis.

MTA42 is raised against C-terminus of BRCA2. HeLa cells contain full length BRCA2 whereas Capan-1 cells have a BRCA2 C-terminal truncation.

Anti-BRCA2 [MTA42] Product

Breast Cancer Type 2 susceptibility protein (BRCA2) is a tumour suppressor gene. BRCA2 is involved in the repair of chromosomal damage, specifically in localising Rad51 to double strand breaks. BRCA2 […]

Anti-IFITM3 [IFITM3] Product

Analyses of gene expression of IFN-inducible transmembrane protein (IFITM) levels revealed high levels of expression in early and late intestinal neoplasm in both mice and humans.

Anti-LewisA [PR 5C5] mAb Product

PR 5C5 is useful for histological diagnosis of colon disorders and has wide reactivity with bowel, small intestine, stomach and colo-rectal tumours.

Adapted from Parker et al. 2008. EMBO J; 27(18)

Anti-PCNA [5E6/2] Product

Monoclonal antibody which binds PCNA, a tumour proliferation marker.