Immunofluorescence was performed on human brain cell line (U-138MG) using anti-Cathepsin L [4C11] (A) or a commercially sourced antibody (B)

Anti-Cathepsin L [4C11] Product

It is recognized that many cancer cells secrete cathepsin L to degrade the components of extracellular matrices and basement membranes. This promotes tumor invasion and metastasis.

Anti-HPV18E6 [C1X1] Product

[…] the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively. BF7 can be used for detection of HPV in cervical smears […]

Anti-Cytochrome P450 8B1 [M15-P3B7] Product

Implicated in hepatocellular carcinoma. CYP8B1 is upregulated in primary and metaststic colorectal tumours compared to normal colon mucosa.

Immunohistochemistry

Anti-TIGAR [M2-P4H2] Product

This suggests a role for TIGAR in protecting cells from reactive oxygen species that can be DNA damaging and lead to apoptosis.

Primary human keratinocytes

Anti-NSun2 [EF-1] Product

NSun2 is a cytosine-5 RNA methyltransferase of transfer RNAs (tRNAs) and other non-coding RNAs. NSun2 is expressed in various tissues, including skin, brain and testis. Expression of Nsun2 is up-regulated […]

Anti-Desmoglein [33-3D] Product

33-3D is directed against desmoglein in mammalian tissues, tumours and cultured cells.

Anti-vFlip [6/14] Product

This antibody can be used to detect expression of latent vFLIP in KSHV infected cells and tumours and for examining the role of vFLIP in cell signaling.

Anti-SPAG1 [10G1/2] Product

[…] extent and intensity of SPAG1 expression has been shown to be associated with stage and tumour nodal status and this has led to the suggestion that SPAG1 is a novel […]