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Mouse models

CancerTools provides a diverse range of mouse models from leading cancer institutes and universities worldwide. These include knockout and transgenic mice to study gene function and for preclinical drug validation in cancer, Duchenne muscular dystrophy, and neurological diseases.

Showing 1–25 of 152 results

Cat. #

Tool Name

151442

Cat. #:	151442
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	a5 integrin, b1 integrin

151443

GSTP1GSTP2 KO Mouse

Cat. #:	151443
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Glutathione Transferase P1 and P2 (GSTP1, GSTP2)
Application:	Lung and skin tumourigenesis modeling; drug metabolism; drug toxicity studies

151444

Cat. #:	151444
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	MEK1

151454

Bmx Cre ERT2 Mouse

Cat. #:	151454
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	BMX, CreERT2

151467

Cat. #:	151467
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	p23

151474

DR3-/- KO Mouse

Cat. #:	151474
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	DR3 (Death Domain Receptor 3)
Application:	In vivo studies of DR3-induced apoptosis & function; in vivo studies of negative T cell selection and development

151475

Raf KI D486A Mouse

Cat. #:	151475
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Raf1 D486A (oncogenic mutant)

151476

Raf-/- KO Mouse

Cat. #:	151476
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Raf1+/- heterozygous knockout

151477

Raf-1FF/FF knockin mouse

Cat. #:	151477
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Raf1 Y340F Y341F (inactive mutant)

151478

Cat. #:	151478
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Constitutively active MAP/ERK kinase 1 (caMEK1) mutant

151481

DLL1 Floxed Mouse

Cat. #:	151481
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Delta like-1 (Dll1)

151482

Jagged1 Floxed Mouse

Cat. #:	151482
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Jagged1 (Jag1)

151502

CyclinD1-/- KO Mouse

Cat. #:	151502
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Cyclin D1

151518

Cat. #:	151518
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Interferon-g (IFNg)

151519

Cat. #:	151519
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	BRaf V600E (oncogenic mutant)

151520

CDH5(PAC)CreERT2 Mouse

Cat. #:	151520
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Estrogen receptor (ERT2) under the vascular endothelial cadherin (Cdh5(PAC)) promoter.

151534

Pdgfrb-Cre Mouse

Cat. #:	151534
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Cre recombinase under Pdgfrb promoter

151549

Cat. #:	151549
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Alpha3 intergrin, beta1 integrin

151550

Integrin a6b4 Mouse

Cat. #:	151550
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Alpha6Beta4 Integrin

151551

Cat. #:	151551
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Alpha2 intergrin, beta1 integrin

151552

Cat. #:	151552
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Lymphocyte Function-associated Antigen-1 (LFA1)

151553

Pik3ca RBD mutant Mouse

Cat. #:	151553
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Phosphoinositide 3-Kinase C alpha (PI 3kinase) / p110alpha mutant (disrupted Ras interaction)

151554

Cat. #:	151554
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Elk4 / SAP-1

151555

Cat. #:	151555
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Human MUC1 (mucin-like protein 1) / PEM (polymorphic epithelial mucin)

151556

Cat. #:	151556
Sub-type:	Mouse
Availability:	8-10 weeks
Target:	Uracil-DNA Glycosylase (UNG)

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