Cat. #161805
UM-UC-6 (Human Bladder Transitional Cell Carcinoma) Cell Line
Cat. #: 161805
Availability: 8-10 weeks
Organism: Human
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: H. Grossman ; Anita Sabichi
Institute: University of Michigan
Primary Citation: Grossman et al. 1984. J Urol. 132(4):834-7. PMID: 6471236;Sabichi et al. 2006. J Urol. 175(3 Pt 1):1133-7. PMID: 16469639.
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: UM-UC-6 (Human Bladder Transitional Cell Carcinoma) Cell Line
- Alternate name: UM-UC6; UMUC6; UC-6; University of Michigan-Urothelial Carcinoma-6
- Cancer: Genitourinary cancer
- Research fields: Cancer
- Organism: Human
- Growth properties: Adherent
- Crispr: No
- Description: UM-UC-6 is patient-derived urothelial carcinoma cell line, it was established from a bladder transitional cell carcinoma obtained by a transurethral resection from a male patient. This cell line is tumorigenic in athymic nude mice. The UM-UC panel of urothelial carcinoma is a diverse range of 11 patient derived cell lines developed by the university of Michigan that have been well-categorised in the literature. These cells were assessed for their susceptibility to adenoviral mediated gene delivery, tumour growth in nude mice and differences in genetic alterations
Handling
- Growth medium: Dulbecco's modified Eagle's medium (DMEM) containing 10% heat inactivated Fetal Bovine Serum (FBS) and were supplemented with 1% penicillin and streptomycin
- Temperature: 37°C
- Atmosphere: 5% CO2
- Shipping conditions: Dry ice
- Storage conditions: Liquid Nitrogen
- Cultured in antibiotics: Penicillin, Streptomycin
References
- Grossman et al. 1986. J Urol. 136(5):953-9. PMID: 3761468
- Sabichi et al. 2006. J Urol. 175(3 Pt 1):1133-7. PMID: 16469639
- Park et al. 2008. J Natl Cancer Inst. 100(19):1401-11. PMID: 18812553
- Chiong et al. 2009. J Urol. 181(6):2737-45. PMID: 19375735
- Guo et al. 2013. J Pathol. 230(1):17-27. PMID: 23401075
- Earl et al. 2015. BMC Genomics. 16:403. PMID: 25997541
- Nickerson et al. 2017. Oncogene. 36(1):35-46. PMID: 27270441
- Zuiverloon et al. 2018. Bladder Cancer. 4(2):169-83. PMID: 29732388
