Cat. #153754
THUECa Cell Line
Cat. #: 153754
Unit size: 1x10^6 cells / vial
Availability: 3-5 days
Organism: Human
Disease: Neisseria gonorrhoeae infection
Model: Immortalised Line
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Michael Apicella
Institute: The University of Iowa
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: THUECa Cell Line
- Organism: Human
- Disease: Neisseria gonorrhoeae infection
- Model: Immortalised Line
- Conditional: No
- Description: This transformed human urethera epithelial cell line was developed to study the invasion of Neisseria gonorrhoeae in urethral epithelial cells during gonococcal infection in men.This cell line is phenotypically similiar and responds to gonococcal infection similar to primary cells based on immunofluorescence microscopy data. Cells stain positive for cytokeratin demonstrating immortalized cells are keratinocytes. Human asialoglycoprotein receptor expression and, IL-6 and IL-8 levels are increased after gonococcal infection similar to primary cells. This cell line is CD14 negative.
- Production details: This cell line was derived from primary urethral epithelial cells (obtained from 15 male patients) immortalized by transduction with a retroviral vector expressing human papillomavirus E6E7 genes.
Target Details
- Target: Transformed Human Urethra Epithelial Cell line; Sexually transmitted diseases (STIs)
Handling
- Format: Frozen
- Growth medium: Prostate Epithelial Cell Growth Medium (PrEGM). Cells grow best on collagen-free lab plastic.
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
