
NC-m4 cell line
Organism: Mouse
Tissue: Skin
Disease: Non-cancer
Model: Immortalised non-cancerous cell lines
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Elena Sviderskaya
Institute: St. George's University London
Primary Citation: Sviderskaya EV, et al. FASEB J. 2009 Sep;23(9):3179-92. PMID: 19447881
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: NC-m4 cell line
- Research fields: Tissue-specific biology
- Organism: Mouse
- Gender: Unspecified
- Tissue: Skin
- Disease: Non-cancer
- Morphology: Small, oval-fusiform
- Growth properties: Adherent
- Model: Immortalised non-cancerous cell lines
- Crispr: No
- Conditional: No
- Description: The nc-m4 and -m6 cell lines are neural crest-like stem cells derived from Dock7m/Dock7m C57BL6/J mice. These lines retain pluripotency, can proliferate indefinitely, and can be differentiated into melanoblasts, melanocytes, pre-Schwann cells, sensory neurons and chondrocytes. These lines may be useful for developmental studies.
- Application: Melanocyte cell biology
- Biosafety level: BSL1
Applications
- Application: Melanocyte cell biology
Handling
- Growth medium: RPMI + Newborn Calf Serum (NCS) (10%) + TPA (2 nM)
- Storage conditions: liquid N2
References
- Sviderskaya EV, et al. FASEB J. 2009 Sep
- 23(9):3179-92. PMID: 19447882
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