Melb-p3 cell line
Organism: Mouse
Tissue: Skin
Disease: Non-cancer
Model: Immortalised non-cancerous cell lines
£575.00
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Contributor
Inventor: Elena Sviderskaya
Institute: St. George's University London
Primary Citation: Sviderskaya EV, et al. J Invest Dermatol. 1997 Jan;108(1):30-4. PMID: 8980282
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Melb-p3 cell line
- Cancer: N/A
- Research fields: Tissue-specific biology
- Organism: Mouse
- Gender: Unspecified
- Tissue: Skin
- Disease: Non-cancer
- Morphology: Small, oval-fusiform
- Growth properties: Adherent
- Model: Immortalised non-cancerous cell lines
- Crispr: No
- Conditional: No
- Description: The melb-p3 and melb-4 lines are immortal melanoblast cell lines derived from Oca2p-cp/Oca2p-25H CH3 mice. These melanoblasts can grow in melanocyte growth medium without differentiating to melanocytes. This melanoblast line may be useful for developmental studies and, as melanoblasts display mechanisms similar to tumour cells (migration to and invasion of the epidermis) they may be a useful tool in studies of melanoma development. Melanocyte lines (melan-p1 and melan-p2) derived from Oca2p-cp/Oca2p-25H CH3 mice are also available from Cancer Tools.
- Application: Melanocyte cell biology
- Biosafety level: BSL1
Applications
- Application: Melanocyte cell biology
Handling
- Growth medium: RPMI + FBS (10%) + TPA (200 nM) + CT (200 pM) + 2ME (100 µM)
- Storage conditions: liquid N2
References
- Sviderskaya EV, et al. J Invest Dermatol. 1997 Jan
- 108(1):30-4. PMID: 8980283
