Melan-m3 cell line

Organism: Mouse

Tissue: Skin

Disease: Non-cancer

Model: Immortalised non-cancerous cell lines

£575.00

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Contributor

Inventor: Elena Sviderskaya

Institute: St. George's University London

Primary Citation: Sviderskaya EV, et al. Genetics. 1998 Jan;148(1):381-90. PMID: 9475748

Tool Details

Applications

Handling

References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

Name: Melan-m3 cell line
Research fields: Tissue-specific biology
Organism: Mouse
Gender: Unspecified
Tissue: Skin
Disease: Non-cancer
Morphology: Small, oval-fusiform
Growth properties: Adherent
Model: Immortalised non-cancerous cell lines
Crispr: No
Conditional: No
Description: The melan-m1, -m2 and -m3 cell lines are immortal melanocyte cell lines derived from the skin of neonatal Dock7m/Dock7m C57BL6/J mice. The misty mutation in melanocytes results in reduced proliferation and increased dendricity and pigmentation. These melanocytes are a useful tool for studies of pigment cell biology. Neural crest-like stem cells (NC-m4 and NC-m6) and melanoblast lines (melb-m5) derived from misty mice are also available from Cancertools.org.
Application: Melanocyte cell biology
Biosafety level: BSL1

Applications

Application: Melanocyte cell biology

Handling

Growth medium: RPMI + FBS (10%) + TPA (200 nM) + CT (200 pM) + 2-mercaptoethanol (2ME) (100 µM)
Storage conditions: liquid N2

References

Sviderskaya EV, et al. Genetics. 1998 Jan
148(1):381-90. PMID: 9475749