Antibody for TMEM59, also known as transmembrane protein 59. TMEM59 has been shown to modulate ectodomain shedding of the amyloid precursor protein (APP). Its expression is linked to cancer development and prognosis in some cancer types including bone cancer.
| Institute |
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| Helmholtz Munich Core Facility Monoclonal Antibodies |
| Cat. #: | 162381 |
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| Tool sub type: | Primary antibody |
| Research Fields: | Cancer;Cell biology;Cell signaling and signal transduction |
| Application: | WB |
| Target: | TMEM59, C-terminus |
| Reactivity: | Human |
| Clone: | 7C6-4E5 |
| Host: | Rat |
| Class: | Monoclonal |
| Primary citation: | Ullrich et al. 2010. J Biol Chem. 2: 285(27):20664-74. PMID: 20427278 |
| Alternate name: | Anti TMEM59, C-terminus monoclonal antibody (clone 7C6-4E5) |
|---|---|
| Product description: | Antibody for TMEM59, also known as transmembrane protein 59. TMEM59 has been shown to modulate ectodomain shedding of the amyloid precursor protein (APP). Its expression is linked to cancer development and prognosis in some cancer types including bone cancer. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Immunogen: | GST fusion protein of amino acids 261–323 of TMEM59 |
| Target background: | TMEM59, also known as transmembrane protein 59, has been shown to modulate ectodomain shedding of the amyloid precursor protein (APP). Its expression is linked to cancer development and prognosis in some cancer types including bone cancer. |
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| References: |
Ullrich et al. 2010. J Biol Chem. 2: 285(27):20664-74. PMID: 20427278 |
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