Cor 10G11/7 is an excellent tool for the visualisation of chromosomes in meiotic spreads.
| Inventor | Institute |
|---|---|
| Madalena Tarsounas | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| Cat. #: | 151270 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Genetics |
| Application: | IF ; ELISA ; IHC ; IF ; WB |
| Target: | Synaptonemal Complex Protein 3 (SCP3; COR1) |
| Reactivity: | Hamster ; Mouse ; Zebrafish |
| Clone: | Cor 10G11/7 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Cor 10G11/7 is an excellent tool for the visualisation of chromosomes in meiotic spreads. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | Hamster COR1/SCP3 protein (expressed as 6x His fusion in bacteria and purified on a Talon under denaturing conditions). |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | SCP3 (murine and human) / COR1 (hamster) is a component of the meiotic chromosome cores. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | DMEM + 5% FCS |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Verver et al. 2013. Cell Death Dis. 4:e749. PMID: 23907463. Role for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis. Yamaguchi et al. 2013. Cell Res. 23(3):329-39. PMID: 23399596. Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming. Heaney et al. 2012. Development. 139(9):1577-86. PMID: 22438569. Germ cell pluripotency, premature differentiation and susceptibility to testicular teratomas in mice. Tarsounas et al. 2004. Cell. 117(3):337-47. PMID: 15109494. Telomere maintenance requires the RAD51D recombination/repair protein. |
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