Cat. #157668
Anti-PSMA (3F11) mouse
Cat. #: 157668
Sub-type: Primary antibody
Unit size: 100 ug
Target: glutamate carboxypeptidase II (amino acids 226-243)
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Dog ; Human ; Mouse ; Pig ; Rat
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Institute of Biotechnology CAS
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-PSMA (3F11) mouse
- Alternate name: Glutamate carboxypeptidase II; GCPII; NAALADase; FOLH1; Folate Hydrolase 1; N-Acetylated Alpha-Linked Acidic Dipeptidase 1; Prostate Specific Membrane Antigen; PSMA
- Research fields: Cancer;Metabolism
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Dog ; Human ; Mouse ; Pig ; Rat
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: GCPII reveals glutamate carboxypeptidase activity that is responsible for uptake of folate by intestine, moreover, it participates on regulation of neurotransmission via hydrolysis of the neuropeptide N-acetyl-aspartyl-glutamate in central nervous system. GCPII is expressed in several tissues including prostate epithelium, kidney, small intestine and nervous system. Disregulation of GCPII activity could be connected with hyperhomocysteinemia and various neuro-pathological conditions including glutamate excitotoxicity. GCPII stays as a leading biomarker of prostate cancer due to huge upregulation of its expression in tumor tissue.
- Immunogen: human GCPII extracellular domain
- Immunogen uniprot id: Q04609
- Isotype: IgG1 kappa
Target Details
- Target: glutamate carboxypeptidase II (amino acids 226-243)
- Target background: GCPII reveals glutamate carboxypeptidase activity that is responsible for uptake of folate by intestine, moreover, it participates on regulation of neurotransmission via hydrolysis of the neuropeptide N-acetyl-aspartyl-glutamate in central nervous system. GCPII is expressed in several tissues including prostate epithelium, kidney, small intestine and nervous system. Disregulation of GCPII activity could be connected with hyperhomocysteinemia and various neuro-pathological conditions including glutamate excitotoxicity. GCPII stays as a leading biomarker of prostate cancer due to huge upregulation of its expression in tumor tissue.
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
References
- Novkov et al. 2017. Prostate. 77(7):749-764. PMID: 28247415.
