#161730

Anti-KPNB1

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Cat. #161730

Anti-KPNB1

Cat. #: 161730

Sub-type: Primary antibody

Target: Karyopherin Subunit Beta 1 (KPNB1)

Class: Monoclonal

Application: IHC;IF; Electron microscopy (EM); IP; WB; Biotinylation by Antibody Recognition (BAR), ELISA; Proximity ligation assay (PLA)

Reactivity: Human, mouse, rat, bovine

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Michael Fainzilber, Ida Rishal, Ella Doron-Mandel, Stefanie Alber, Didi-Andreas Song

Institute: Weizmann Institute of Science

Primary Citation: Didi-Andreas Song, et al. 2022. Mol Cell Proteomics. 21(11):100418. PMID: 36180036

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-KPNB1
  • Alternate name: mAbKPNB1-301-320
  • Cancer: Gynaecologic cancer;Neurological cancer
  • Research fields: Cell signaling and signal transduction;Genetics
  • Clone: KPNB1
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: No
  • Molecular weight: 97.170 kDa
  • Reactivity: Human, mouse, rat, bovine
  • Host: Mouse
  • Disease: Cancer
  • Application: IHC;IF; Electron microscopy (EM); IP; WB; Biotinylation by Antibody Recognition (BAR), ELISA; Proximity ligation assay (PLA)
  • Description: Anti importin beta1 (KPNB1) is a nucleocytoplasmic transport factor with critical roles in both cytoplasmic and nucleocytoplasmic transport. It has been implicated in cancer in a number of studies, including glioblastoma, epithelial ovarian cancer, gastric cancer and cervical cancer. It was also shown to be important in axonal injury signalling activate regeneration programs in neuronal cell bodies
  • Immunogen: The antibody was raised against full-length recombinant mouse importin ?1 protein (UniProt accession # P70168). The protein included an N-terminal His-tag and was produced in yeast (MyBioSource: cat # MBS955236).
  • Immunogen uniprot id: Q99KM9
  • Isotype: IgG2b
  • Additional notes: The epitope sequence has been mapped to a 20 amino acid linear sequence comprising residues 301-320 of human KPBN1. A synthetic peptide with this sequence can be used as a blocking control for antibody specificity

Target Details

  • Target: Karyopherin Subunit Beta 1 (KPNB1)
  • Molecular weight: 97.170 kDa
  • Target background: Importin ?1 (KPNB1) is a nucleocytoplasmic transport factor with critical roles in both cytoplasmic and nucleocytoplasmic transport

Applications

  • Application: IHC;IF; Electron microscopy (EM); IP; WB; Biotinylation by Antibody Recognition (BAR), ELISA; Proximity ligation assay (PLA)

Handling

  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: 4° C

References

  • Didi-Andreas Song, et al. 2022. Mol Cell Proteomics. 21(11):100418. PMID: 36180036