#151384

Anti-HRX [HRX107]

Cat. #151384

Anti-HRX [HRX107]

Cat. #: 151384

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: Histone-lysine N-methyltransferase (HRX, MLL, ALL1, Htrx)

Class: Monoclonal

Application: ChIP ; IHC ; IF ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Jacqueline Cordell

Institute: University of Oxford

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-HRX [HRX107]
  • Research fields: Cancer;Genetics
  • Clone: HRX107
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ChIP ; IHC ; IF ; WB
  • Description: The HRX gene (also called MLL, ALL-1 or Htrx) located to chromosome band 11q23 is associated with specific subsets of acute Lukaemia through translocations that that result in its fusion with a variety of heterologous partners
  • Immunogen: Synthetic peptides corresponding to 839-854 of the HRX protein
  • Isotype: IgM
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: Histone-lysine N-methyltransferase (HRX, MLL, ALL1, Htrx)
  • Target background: The HRX gene (also called MLL, ALL-1 or Htrx) located to chromosome band 11q23 is associated with specific subsets of acute Lukaemia through translocations that that result in its fusion with a variety of heterologous partners

Applications

  • Application: ChIP ; IHC ; IF ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Mueller et al. 2009. PLoS Biol. 7(11):e1000249. PMID: 19956800.
  • Misguided transcriptional elongation causes mixed lineage leukemia.
  • Butler et al. 1997. Blood. 89(9):3361-70. PMID: 9129043.
  • The HRX proto-oncogene product is widely expressed in human tissues and localizes to nuclear structures.