#160587

Anti-hEMILIN2 [hEMIL2]

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Cat. #160587

Anti-hEMILIN2 [hEMIL2]

Cat. #: 160587

Sub-type: Primary antibody

Unit size: 100 ug

Target: hEMILIN2

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Alfonso Colombatti ; Maurizio Mongiat ; Roberto Doliana ; Maria Teresa Mucignat

Institute: National Cancer Institute CRO - Aviano

Tool Details
Target Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-hEMILIN2 [hEMIL2]
  • Research fields: Apoptosis and autophagy;Cancer;Cell biology;Cell signaling and signal transduction
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: Emilin-2 (Elastin Microfibril Interface Located proteIN) is an extracellular matrix glycoprotein. Is part of a protein family which have been shown to be expressed in smooth muscle and other mesenchymal tissues and is localized at the proximity of elastin and microfibrils. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is involved in regulation of the extrinsic apoptotic pathway, by interacting with death receptors DR4 and DR5 and down-modulates the Wnt signalling pathway. EMILIN2 is also involved in the regulation of angiogenesis and elastogenesis
  • Immunogen: Recombinant human Emilin-2 as immunizing antigen; BALB/c mice as host
  • Recommended controls: IgG2b kappa

Target Details

  • Target: hEMILIN2
  • Tissue cell line specificity: IgG2b kappa
  • Target background: Emilin-2 (Elastin Microfibril Interface Located proteIN) is an extracellular matrix glycoprotein. Is part of a protein family which have been shown to be expressed in smooth muscle and other mesenchymal tissues and is localized at the proximity of elastin and microfibrils. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is involved in regulation of the extrinsic apoptotic pathway, by interacting with death receptors DR4 and DR5 and down-modulates the Wnt signall...

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Storage conditions: Store at 2 - 8° C or aliquots at -20° C. Avoid repeated freeze-thaw cycles
  • Shipping conditions: Shipping at 4° C

Related Tools

  • Related tools: Anti-mEMILIN1 [mEMIL] monoclonal antibody ; Anti-hEMILIN1 [hEMIL1] monoclonal antibody ; Anti-mMMRN2 [mMMRN2] monoclonal antibody

References

  • Marastoni et al. 2014. J Pathol. 232(4):391-404. PMID: 24374807.
  • Mongiat et al. 2010. Neoplasia. 12(4):294-304. PMID: 20360940.
  • Mongiat et al. 2007. Mol Cell Biol. 27(20):7176-87. PMID: 17698584.