#153919

Anti-Ferret immunoglobulin (IgK) [GK1-1-4-B10]

Cat. #153919

Anti-Ferret immunoglobulin (IgK) [GK1-1-4-B10]

Cat. #: 153919

Unit size: 100 ug

Availability: 10-12 weeks

Target: Ferret Immunoglobulin

Class: Monoclonal

Application: WB ; ELISA ; FACS

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ted Ross

Institute: University of Georgia

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Ferret immunoglobulin (IgK) [GK1-1-4-B10]
  • Alternate name: Ig
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Host: Mouse
  • Application: WB ; ELISA ; FACS
  • Description: The domestic ferret (Mustela putorius furo) serves as an animal model for the study of several viruses that cause human disease, most notably influenza. Despite the importance of this animal model, characterization of the immune response by flow cytometry (FCM) is severely hampered due to the limited number of commercially available reagents. To begin to address this unmet need and to facilitate more in-depth study of ferret B cells including the identification of antibody-secreting cells, eight unique murine monoclonal antibodies (mAb) with specificity for ferret immunoglobulin (Ig) were generated using conventional B cell hybridoma technology. These mAb were screened for reactivity against ferret peripheral blood mononuclear cells by FCM and demonstrate specificity for CD79Î?+ B cells. Several of these mAb are specific for the light chain of surface B cell receptor (BCR) and enable segregation of kappa and lambda B cells, and represent great improvement over polyclonal anti-ferret Ig reagents.
  • Immunogen: Ferret IgG and IgM
  • Isotype: IgG1 kappa

Target Details

  • Target: Ferret Immunoglobulin
  • Target background: The domestic ferret (Mustela putorius furo) serves as an animal model for the study of several viruses that cause human disease, most notably influenza. Despite the importance of this animal model, characterization of the immune response by flow cytometry (FCM) is severely hampered due to the limited number of commercially available reagents. To begin to address this unmet need and to facilitate more in-depth study of ferret B cells including the identification of antibody-secreting cells, eight unique murine monoclonal antibodies (mAb) with specificity for ferret immunoglobulin (Ig) were generated using conventional B cell hybridoma technology. These mAb were screened for reactivity against ferret peripheral blood mononuclear cells by FCM and demonstrate specificity for CD79Î?+ B cells. Several of these mAb are specific for the light chain of surface B cell receptor (BCR) and enable segregation of kappa and lambda B cells, and represent great improvement over polyclonal anti-ferret Ig reagents.

Applications

  • Application: WB ; ELISA ; FACS

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

References

  • 29079697