Cat. #161699
Anti-CD14 monoclonal antibody [GRS1]
Cat. #: 161699
Sub-type: Primary antibody
Availability: 3-4 weeks
Target: CD14
Class: Monoclonal
Application: FACS; IHC; ELISA; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Francisco Ruíz-Cabello Osuna,Miguel Ángel López-Nevot and Federico Garrido Torres-Puchol, Susana Pedrinaci Rodriguez
Institute: Virgen de las Nieves University Hospital, The Andalusian Health Service
Primary Citation: Knapp et al. 1990. Immunology 1991. PMCID: PMC1384357
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD14 monoclonal antibody [GRS1]
- Cancer: Blood cancer
- Research fields: Cancer
- Clone: GRS1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Molecular weight: 53-55 kDa
- Reactivity: Human
- Host: Mouse
- Application: FACS; IHC; ELISA; WB
- Description: The CD14 antigen is a glycosylphosphatidylinositol-linked single-chain surface membrane glycoprotein with a molecular weight of 53-55 kDa. It functions as a high-affinity receptor for the lipopolysaccharide (LPS) and LPS-binding protein (LBP) complex. It is found on cells of the myelomonocytic lineage. CD14 antigen is highly expressed on monocytes and macrophages, and weakly expressed on neutrophils. It is also weakly expressed on B-lymphocytes, but absent on T- and NK-lymphocytes, erythrocytes and platelets. It is found on Langerhans cells, follicular dendritic cells and histiocytes. GRS1 is a mouse monoclonal antibody of the IgG1 isotype.
- Immunogen: U937 cell line
- Isotype: IgG1
- Recommended controls: monocytes, macrophages
Target Details
- Target: CD14
- Molecular weight: 53-55 kDa
Applications
- Application: FACS; IHC; ELISA; WB
Handling
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Knapp et al. 1990. Immunology 1991. PMCID: PMC1384357