#153479

Anti-C-kit (CD117) [2C11]

Cat. #153479

Anti-C-kit (CD117) [2C11]

Cat. #: 153479

Sub-type: Primary antibody

Unit size: 100 ug

Target: C-kit

Class: Monoclonal

Application: FACS ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: A*STAR Accelerate Technologies Pte Ltd

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-C-kit (CD117) [2C11]
  • Alternate name: C Kit antibody, c-Kit antibody, CD117 antibody
  • Research fields: Cancer;Immunology
  • Clone: 2C11
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; WB
  • Description: C-kit, also known as CD117, is expressed on the surface of hematopoietic stem cells. C-kit is a receptor tyrosine kinase that is overexpressed in > 70% of gastrointestinal stromal tumors (GISTs).
  • Immunogen: GST-fusion protein containing 315-519 residues of human c-kit. c-kit. This region is in the extracellular domain of c-kit.
  • Isotype: IgG1
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: C-kit
  • Target background: C-kit, also known as CD117, is expressed on the surface of hematopoietic stem cells. C-kit is a receptor tyrosine kinase that is overexpressed in > 70% of gastrointestinal stromal tumors (GISTs).

Applications

  • Application: FACS ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Bellone et al. 2001. Cancer Res. 61(5):2200-6. PMID: 11280787.
  • Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential.