#157693

Anti-Bordotella avium 41-kDa Surface Protein [1G12]

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Cat. #157693

Anti-Bordotella avium 41-kDa Surface Protein [1G12]

Cat. #: 157693

Unit size: 100 ug

Target: Bordotella avium 41-kDa Surface Protein

Class: Monoclonal

Application: ELISA ; IF ; WB

Reactivity: Bordotella avium

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: University of Georgia

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Bordotella avium 41-kDa Surface Protein [1G12]
  • Research fields: Microbiology
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 41
  • Reactivity: Bordotella avium
  • Host: Mouse
  • Application: ELISA ; IF ; WB
  • Description: Bordotella avium, a Gram-negative, aerobic and motile bacterium, is the causative agent of turkey coryza, an economically-impacting disease that can also infect other birds. The bacterium has been isolated from individuals with cystic fibrosis, although the contribution of the organism to the disease is still unclear.B. avium shares several virulence factors with human pathogens. A 41 kDa surface protein of B. avium is strongly associated with the organism’s virulence and ability to attach to tracheal mucosa. Monoclonal antibodies designated 9F8, 1G12 and 14G8 immunoprecipitate the 41kDa protein and also inhibited HA of guinea pig erythrocytes by B. avium. These antibodies have the potential to be used in the development of therapeutic and/or diagnostic tools.
  • Immunogen: CsCl-purified protein from B. avium 002/S isolate
  • Myeloma used: Sp2/0
  • Recommended controls: IgG1 kappa

Target Details

  • Target: Bordotella avium 41-kDa Surface Protein
  • Molecular weight: 41
  • Target background: Bordotella avium, a Gram-negative, aerobic and motile bacterium, is the causative agent of turkey coryza, an economically-impacting disease that can also infect other birds. The bacterium has been isolated from individuals with cystic fibrosis, although the contribution of the organism to the disease is still unclear.B. avium shares several virulence factors with human pathogens. A 41 kDa surface protein of B. avium is strongly associated with the organism’s virulence and ability to attach to tracheal mucosa. Monoclonal antibodies designated 9F8, 1G12 and 14G8 immunoprecipitate the 41kDa protein and also inhibited HA of guinea pig erythrocytes by B. avium. These antibodies have the potential to be used in the development of therapeutic and/or diagnostic tools.

Applications

  • Application: ELISA ; IF ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

References

  • Harrington et al. 2009. Emerg Infect Dis. 15(1):72-4. PMID: 19116056.
  • Moore et al. 1994. Avian Dis. 38(2):218-24. PMID: 7980267.
  • Moore et al. 1994. Avian Dis. 38(1):50-8. PMID: 8002900.
  • Domingo et al. 1992. Avian Dis. 36(3):707-13. PMID: 1358051.
  • Jackwood et al. 1991. Avian Dis. 35(3):496-504. PMID: 1953575.