Lung cancer Page

[…] models for studying the effects of KRAS-G12C inhibition on the tumour microenvironment and anti-tumour immunity. KPAR cell lines, developed from tumours in an immunogenic syngeneic transplantation model of KRAS-mutant lung […]

KPAR-G12C Cell Line Product

KPAR-G12C Cell Line: Mouse models of mutant KRAS-driven lung cancer with an elevated tumour mutational burden by expressing the human DNA cytosine deaminase, APOBEC3B, to mimic the mutational signature […]

KPAR1.3 Cell Line Product

Mouse models of mutant KRAS-driven lung cancer with an elevated tumour mutational burden by expressing the human DNA cytosine deaminase, APOBEC3B